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Why fasting bolsters brain power: Mark Mattson at TEDxJohnsHopkinsUniversity

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Mark Mattson is the current Chief of the Laboratory of Neurosciences at the National Institute on Aging. He is also a professor of Neuroscience at The Johns Hopkins University. Mattson is one of the foremost researchers in the area of cellular and molecular mechanisms underlying neurodegenerative disorders such as Alzheimer's Disease, Parkinson's Disease, and amyotrophic lateral sclerosis. In the spirit of ideas worth spreading, TEDx is a program of local, self-organized events that bring people together to share a TED-like experience. At a TEDx event, TEDTalks video and live speakers combine to spark deep discussion and connection in a small group. These local, self-organized events are branded TEDx, where x = independently organized TED event. The TED Conference provides general guidance for the TEDx program, but individual TEDx events are self-organized.* (*Subject to certain rules and regulations)
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Текстовые комментарии (2296)
Air-Grip Biker (4 дня назад)
he's not very good at talking.. why did He have to do it? pls go and bolster ur brain more sir
Chouchou Ccc (4 дня назад)
Thats why we muslim fast...my brother fast each thursday foir years now
Ashton On Piano (6 дней назад)
Hi Mr Pang
Franck Boistel (7 дней назад)
Evidence! Human being has evolve with intermittent fasting, most people around this planet still eat two or one meal per day, probably not by choice though....We eat too much because we can....
Jerry Minno (8 дней назад)
We used to live like Hunters from sparse lands, quite simple really when you think about it.
Jerry Minno (8 дней назад)
Wow, were have i been, totally got it, we all have to struggle to survive.. So informative👍
MissNebulosity (8 дней назад)
I didn't know TED talks could be conducted like a boring powerpoint presentation. *This guy has some seriously good info to present,* but man his presentation style puts me to sleep.
N L (9 дней назад)
we  treat rodents poorly sickening
K Kakuszi (10 дней назад)
Hi, I just started IF 16 /8 however in the eating window I cannot eat the required calories, as I am not that hungry after the second meal. However we need the minimum whatever calories so our body can function. I can't even eat that in the 8 hour eating window. I am vegan. Any ideas? Thanks
Mahjabeen Malik (18 дней назад)
he seems to be a saint of his time.God Bless you for not selling your knowledge to greedy rich .
Name Name (21 день назад)
Very good lecture. Thank you for sharing.
Dan Hamilton (21 день назад)
I’m going to do it, still I don’t trust a guy with a comb over.
Bernadette Jackson (21 день назад)
Great talk 🖤
Varun M Bhat (22 дня назад)
Mahatma Gandhi stressed on the principles of ahimsa way of life. One of the important aspect is restraining from eating over a period of time. He used it show his incorporation with the British.
xi wu (24 дня назад)
Maybe Job's "Stay hungry" is not only mental state, but physical practice also.
SpeedStriker (29 дней назад)
12:17 If you're not going to go into the details about it, then I will: MITOCHONDRIA IS THE POWERHOUSE OF THE CELL!
Joseph Sliwa (30 дней назад)
So true...I just wanted to shed a few lbs for a camera shoot and found that my thoughts, memory and fitness greatly enhanced by doing a water fast. Thanks for this message that confirms my experience.
Make Humanity Great Again (1 месяц назад)
I wonder the age of this gentleman. *Edit:* Born 1957. Thus around 57 at the time of this talk.
Рамазан Алишихов (1 месяц назад)
Prophet Muhammad (may peace be upon him) said "If you khow all benefits of fasting you will fast every day all the year around". It is obligatory for muslims to fast each day during one sacred month. And desirable to fast each monday and thursday.
hbk711x (1 месяц назад)
ppl increase life spans of animals by reducing energy intake! fasting is good for brains. plato said he fasted for physical and mental efficiency! fasting gives you a metabolism shift, glycogen storage in liver ussually takes 12 hours to deplete but ususally never does with 3 meals a day unless you excercise. glycogen when fasting burns and you produce ketone bodies which are very good for your brain! if you eat only within 8 hour time period, evidence shows this time window it will have health benefits, long enough to shift the energy metabolism! fasting bolsters brain power. in development and in adults nuerons are generated from stem cells grow out axons and dendrites and form connection and communicate. brain ages sometimes succesffuly and in tact, others don't and gain diseases. Fasting is a challenge and brain responds by activating adaptive stress response pathways and cope with disease. this guys asks does it make sense evolutionary, why does it happen? you don't want your brain to shut down if you are hungry. some of these changes also happens with excercise. Hard excercise is a challenge! When you get done you feel great. both excercise and fasting intermittent both increase nuerotrofic proteins in the brains. f jeff promote connections of nuerons and connection of synapsis! fgf and bdnf both grow! cognitive challenges! it can create new nerve cells from hyppocampus. Romans would starve ppl with epiletic. Ketone suppress epileptic seizures. Ketone give alt. fuel and boost energy for nuerons. bdnf can increase mitochondria in nerve cells. nuerons help form more energy! more mitochondria helps nuerons form and create synapsis to form memories. fasting helps nerve cells restore dna! intelectual challenges also. oxidating stress cells repare oxidated damage to dna! theres alot of money in eating 3 times a day! pharmacuetical companies can lose money if ppl are healthy! communication is to improve health. says we use tax payer money, we don't have a profit motive. this is research not done by pharmacuetical industry. its like excercising, you can get used to it like fasting! the days you dont eat you can be more productive!
Juan Gonzalez (1 месяц назад)
I like this video a lot. fasting is a sound choice. but this dude needs a snack.
Dan Fogg (1 месяц назад)
Youd shave it off wouldn’t ya
Burhan Yasin (1 месяц назад)
All the racism in this world at 8:10. This stupidity "scientist" doesn't know the details.
Rethink Science (1 месяц назад)
I fast most of the week , my first meal is around lunch down to 2:30 pm - 17- 19 hours don’t feel hungry at all - not have processed sugars - do have plenty of water and various teas - fantastic results in work productivity and weight lose.
Conor Turk (1 месяц назад)
Great information but poor delivery. I have been doing intermittent fasting for a couple of weeks now, and I love it. It makes my life so much easier. The benefits of it trump any hunger pangs, and I can see myself living like this long term. The amount of money and time I'm saving, not to mention the gradual weight loss and my minor digestive issues all magically disappearing within a day of fasting. It's been great! Although I can't confirm what all the other people are saying about mental clarity and energy. The first week I really did feel great but now I feel how I did prior to fasting (mentally and mood wise). Overall though, it's been worth it. It's easier and cheaper than any other "diet" out there. If you're on the fence about fasting, GO FOR IT!
Bamboor (1 месяц назад)
too bad it's not good for balding T_T
Crisanto Custodio (1 месяц назад)
Jim Carrey really looks old now.
Daniel Attila (1 месяц назад)
No need to torture animals to find out what even the ancients knew. Nothing new here.
Lukas The Infinite (1 месяц назад)
Was he a bit nervous in the end?
Mr. Numi Who (1 месяц назад)
What happened to 'Power Food for the Brain'? (another TEDx talk)... Solution: Try every method you've ever heard of, but in moderation... and in the end, it may all be psychosomatic anyway...
GamingTV (1 месяц назад)
thing is, when we eat full meals, it alters and changes both our mental states and our brain chemicals depending what we eat, and how much we eat, so if we limit what we eat, we free our minds from these chemical changes to can occur during the new chemical transitions of the new meals our body absorbs
robert hingston (1 месяц назад)
Also metal benefits.. Helps you discipline yourself mentally... denied gratification is a good thing.. even 1 day of week is harmless to most people .. but yes talk to your doctor if your on medication etc .. etc
Bob Houghton (1 месяц назад)
Fasting is so good, you'd never guess this guy is 75 years old.
bcmasur (1 месяц назад)
I recommend Tetris... =) My favorite version is Tetris The Absolute The Grand Master 2 Plus and can be played using MAME... I have some Youtube videos of it, check it out
bcmasur (1 месяц назад)
WTF in the slide says fasting for 2 weeks??? That's impossible!
CHRISTIANNWO (1 месяц назад)
bcmasur, I water fasted for 1 week. It's not as tough as I thought it would be. Next time I wanna do two weeks. The toughest part was the low energy levels between days 3 & 6. I remember on the 7th day, my energy levels were much higher than usual, that I actually exercised (which I'm not supposed to do while fasting). The body is stronger than most people think.
Erica Brohm (1 месяц назад)
It’s so scary how much our world is focused on money. We can’t even trust doctors anymore because they’re not trained for their patients’ best interest, they’re trained to prescribe a pill and make money off of you.
Angela Hite (1 месяц назад)
I've been fasting from 8pm to 2pm for the last 3 months. I've lost a ton of weight and feel so much better!
Genius Idiot (2 месяца назад)
Was gonna fast but watching how he struggles to think and speak made me question the intelligence of such a action.
Kristie Work (2 месяца назад)
Very informative and thought provoking
michael castro (2 месяца назад)
I like this guy. Seems a good man.
Gold Hunter (2 месяца назад)
What they do to those poor mice.
Apophis XO (2 месяца назад)
I believe that there may be many benefits to calorie restrictive diets, but this guy scares me a bit. He does not need to skip any more meals. Wherever it was he intended to go with this, I believe he has arrived. It's over...have a sandwich man!
Michael Neeley (2 месяца назад)
I want to give this guy a makeover so badly
Michael 732 (2 месяца назад)
That's funny. Sometimes its tough to get past stuff like that.
Abhijith Shivaswamy (2 месяца назад)
Thank you.
Anhad Singha (2 месяца назад)
What about the sleeping cycle apart from the 8 hour gap for intermittent fasting or are you talking about the sleep cycle here?
Lord Ozak (2 месяца назад)
What? Haven't he ever heard that if you are skipping breakfast it keeps high cortisol levels for the whole morning that day? They have no profit motive - he says. We are using your money - he says... I tell you : using others money to solve others problems is the less efficient way of spending it.
LiViro1 (2 месяца назад)
Another great way to break ageing: Do a massive combover!
Duggy Dugg (3 месяца назад)
By 2050 the debt will have crashed the economy... We won't have to worry about extending life
Jason Dashney (3 месяца назад)
The beginning part is all about the nonchalantness about the horrors they subject mice to. It's amazing to me how cold people can become in the name of empathy.
ronald phillips (3 месяца назад)
I did a three week fast just drinking real lemon juice the results were a stone lighter and increased cognition.
Michael 732 (2 месяца назад)
Great news. But now I have to google what a stone is?
streetmuggedbypolice (3 месяца назад)
Great talk. But the speaker doesn't exactly look the picture of health. He looks quite..hungry? lol
Paul Davenport (3 месяца назад)
NOW I know where Playdo got its name!
Paul Davenport (3 месяца назад)
I could use a doughnut about now.
Meinung Abundance (3 месяца назад)
I definitely prefer excercise to fasting....:-) Physical activity is also anti-depressing. Fasting is not - on the contrary!
Sean Rupe (3 месяца назад)
Pure truth. Thank you!
Rose Robertson (3 месяца назад)
Lovely attitude support drink physics call artist blend limit yes.
Koula Kremastioti (3 месяца назад)
Stop animal experiments! We send spaceships to outer space for goodness sake! Isn't there any other way to get scientific results?
A C Randleman sports cards (3 месяца назад)
I was a type 2 diabetic. Until I heard about intermittent fasting I can say from my experience it works wonders in 3 months I went from 209 lbs to 172 lb ....cut soda eat healthy and go on 2 or 3 bike rides a week it was a program that put my diabetes into remission in 3 months no meds no finger pricking it works wonders I did the 8 / 16 diet and it changed my life
Danial M (3 месяца назад)
now i know why Islam fasting~
Quazi Roberts (3 месяца назад)
I eat once a month and it has totally changed my life 💀
Christina M. (3 месяца назад)
I practice intermittent fasting, it's really easy! I've never been a three meal a day person.
Mr King (3 месяца назад)
Happy Ramadane ???!!!
Lachezar Kutsarov (3 месяца назад)
WARNING: Health damaging products are being sold in REWE und Rossmann Berlin Central Railway Station Stores! After being warned, the staff refuses to take them off the shelves! I invite the press from Germany and all over the world to join me every time a purchase food or beverage to see what's is going on! And here I would like to make an IMPORTANT NOTE: The fault for the health damaging products lies not with the companies that produced them! The products have been tampered with after the goods have left the premises of the producer! These who do these crimes have nothing to do with the People of Johann Wolfgang von Goethe, Max Planck and the other Great Spirits: they are a sort of Rumanian Gypsies who somehow got through the system and should receive a severe punishment for their crimes!!!
chastity chyld (4 месяца назад)
Awesome commentary 2 the point and informative
Stacey Lee (4 месяца назад)
Rick Kan (4 месяца назад)
This man's hair follicles are starving
justarad (4 месяца назад)
I found it challenging to listen to this guy!
Cousin Eddie Johnson (4 месяца назад)
Super intelligent man but holy nervous. So glad I found this.
linda reboh-king (4 месяца назад)
I believe in everything he is saying, but why does he look so unhealthy
Alpha Geminorum (4 месяца назад)
It's completely obvious to anyone following an IF diet that the food industry, the pharma industry and Republican lawmakers who are invested in those industries are all AGAINST a healthy society. A healthy society doesn't purchase excess amounts of food, or eat massive amounts of calories. A healthy society doesn't stay on pharmas. A healthy society doesn't need expensive health care. By doing IF you are part of the Resistance. Count me as part of that Resistance.
Megan Henry (4 месяца назад)
I do intermittent fasting every day and I can attest to it doing wonders for the brain... and digestive health...which are 1 in the same. I feel even better when I don't eat at all for 24 hours.
Sheila Diuguid (4 месяца назад)
Great content! I agree with you and the research is very interesting!
Karam Levi (4 месяца назад)
X1.5 for sure. Speed it up-
patricia filadelfo (5 месяцев назад)
How can I do when I make challenges exercises, like run and bodybulding early in the morning?
Michel Simard (5 месяцев назад)
Good point yes we can get used to miss food for short time and even enjoy it that my experience
guloguloguy (5 месяцев назад)
GREAT Info!!!! Thanks!!!
agape423 (5 месяцев назад)
I confess that my hand had started to shake in the past. I tried to deny it. I used to fast a lot, somehow I stopped. I started to fast this year, plus getting rid of sugar and the shaking is gone.Aleluyah
Daniel Pincus (5 месяцев назад)
If you eat a diet that does not stress the liver, why is an eight-hour sleep not enough of a fast to achieve these objectives?
sowhatsthescenario (5 месяцев назад)
This dude is in his 60s and looks like me in my 20s
Mark Estrada (5 месяцев назад)
Stick it to the food industry and big pharma... BE HEALTHY! FAST! :)
Wynn Ho (5 месяцев назад)
So what causes my hypoglycemia? Sometimes it doesn't bother me and sometimes it does badly. I know it is nutritionally related, but WHICH vitamin or mineral? I upped my greens and quit caffeine and now I rarely get hypoglycemia. So, is it B9 or magnesium? Btw, many people on CR diets also fast, esp. the 8 hour fast.
Erik Anderson (5 месяцев назад)
I just today finished a four day fast and have never gone this long without food and also, have not felt so good in many years. BTW, I am an epileptic and have noticed a noted decrease in my seizure disorder. This guy couldn't be more right about this topic.
VasilicaCascaval (5 месяцев назад)
this man who speaks has the most need for a brain boost ahahahaha
MrDanielZie (5 месяцев назад)
What kind of tiny sad lecture hall is that to host a ted talk.
Paul nmn (5 месяцев назад)
Boring presenter. Most authors are not fit to present their work .
Chris Winch (5 месяцев назад)
Hey guys, Can i Fast between 12pm-8pm everyday but still enjoy a coffee in the morning? Does it matter how many meals im having? Could i have two BIG meal? Im fairly skinny and dont want to lose weight
Patrick Linden (5 месяцев назад)
Fascinating those kind of baggy shirts are rare today. Hipster warning.
Danny Lee (6 месяцев назад)
Keto diet + intermittent fasting + exercise + quality sleep = winning at life
Yozora Yamikoe (6 месяцев назад)
Isn't it unhealthy to exercise without having breakfast?
Fredrick Nietzsche (6 месяцев назад)
if eating 3 meals a day change to 2. if eating 2 meals a day chane to 1. if eating one meal a day skip one meal a week. point being no matter where you are you can take small achievable steps to save money, time and improve you health. hard to argue with that.
hypnotechno (6 месяцев назад)
Thank God for people like this gentleman. Pure hard science and no profit motive involved in what he is saying. He needs to get smaller shirts though, as the oversized ones make him look a bit malnourished, wish he isn't.
danny iskandar (6 месяцев назад)
I am going to start this tomorrow! remind me after 1 month
TheMasterOfPC (4 месяца назад)
a month passed, what happened?
B. C. (6 месяцев назад)
The science overwhelmingly reveals that the typical diet of three meals a day plus snacks is an unhealthy eating pattern but intermittent fasting is not promoted because of the profit motive. The food and pharmaceutical industries are going to lose money. There is no money to be made on healthy people. So you have to ask yourself a question, is your health more important than the profits of the advertising, food and pharmaceutical industries.
Be Life (6 месяцев назад)
... and how did you induce the diseases and disorders in the mice? ...and where and how did you get the mice that you induced dideases into? Peace and infinite Love to All Be
L Welsh (6 месяцев назад)
If you're feeling slow, fast!
Jaffasoft (6 месяцев назад)
Makes a lot of sense we would have been active in the hunt and gather mode during the more part of evolution and not as lazy as the last few thousand years. We're probably designed to be at our best when hungry and to then activate our brain to be able to best hunt and track down to survive. Hunting is natures exercising and the body at peak performance to survive. This would have been a regular occurrence much more than a modern day in forests etc. Think could possibly the time the body gets rid of and pushes out all the bad stuff. But like time to empty the recycled bins. Ppl won't like fasting on the mass of course because look at them got an obvious society. Should compare this study on the poor countries that can't eat all the time compared to USA.
Febe Grace Bulan (6 месяцев назад)
On my 3rd day of water fast. I try to do minimum 72 hours quarterly. So good for my brain and gut
Daniel Santana (6 месяцев назад)
Thanks Mark, regards from Chile.
Rene Wagoner (6 месяцев назад)
not only the pharmaceutical in the food industry but the fast food industry would be crippled as well obesity is sad USA people are the biggest in the world
Kayla Robertson (7 месяцев назад)
If fasting puts the body under stress and that is what causes all the good changes, the body adapting to the stress of no food, wouldn't that effect wear off as the body becomes used to not receiving food for the longer time? Thus making IF a short term solution for a more active brain and body?

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